Valilactone, an inhibitor of esterase, produced by actinomycetes.
نویسندگان
چکیده
منابع مشابه
Ebelactone, an inhibitor of esterase, produced by actinomycetes.
Sir: We have demonstrated that aminopeptidases, phosphatases and esterases are located not only in cells but also on the cellular membrane of various kinds of animal cells1-3) and that inhibitors of these enzymes modified immune responses4,5). Among these inhibitors, bestatin, amastatin and forphenicine enhanced immune responses, but esterastin which inhibited esterase suppressed immune respons...
متن کاملPepstatin, a new pepsin inhibitor produced by Actinomycetes.
Sir: A specific inhibitor of an enzyme might be useful for the analysis of certain pathogenic phenomena and also perhaps for the treatment of certain diseases. It was postulated that microorganisms because they produce catobolic enzymes may also produce inhibitors of these enzymes. The authors therefore started to search for enzyme inhibitors in microbial culture filtrates and, as reported in p...
متن کاملStructural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes.
In the course of our studies on enzyme inhibitors produced by microorganisms, two potent esterase inhibitors named ebelactone A and B, were isolated from the cultured broth of the strain MG7-G1 which was closely related to Streptomyces aburaviensis1). They were determined to be new members of mycolic acid /3-lactone. As reported in our previous papers2.3), esterastin, an esterase inhibitor prod...
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TA-3037A, a new inhibitor of glutathione S-transferase, has been isolated from the culture broth of Streptomyces sp. TA-3037. The structure of TA-3037A was defined as (Z)-3-benzylidene-3,4-dihydro-2-oxo-2H-1,4-benzoxazine-5-carboxylic acid by an analysis of spectral properties and chemical studies of TA-3037A and its derivatives.
متن کاملGlucuronoyl esterase--novel carbohydrate esterase produced by Schizophyllum commune.
The cellulolytic system of the wood-rotting fungus Schizophyllum commune contains an esterase that hydrolyzes methyl ester of 4-O-methyl-d-glucuronic acid. The enzyme, called glucuronoyl esterase, was purified to electrophoretic homogeneity from a cellulose-spent culture fluid. Its substrate specificity was examined on a number of substrates of other carbohydrate esterases such as acetylxylan e...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1987
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.40.1647